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PEPFAR’s Golden Era Is Over. It Urgently Needs a Five-Year Transition Plan

There is no path back to PEPFAR’s old model, but with political will and skilled leadership, it is possible to navigate PEPFAR’s reduced capabilities and mission, manage current shocks, ensure an orderly handoff, and achieve an accelerated, five-year transition plan.

Critical Questions by Jirair Ratevosian, J. Stephen Morrison, and Katherine E. Bliss — May 16, 2025